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BIOSEB DEVELOPMENT |
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ActiV_Meter: Bioseb's Actimeter for Mice
(Model: ACTIV-METER-M - For Mice)
Our new activity meter (or actimeter) : Activity and Locomotion of rodents (mouse and rat) in the home cage, an accurate and economical instrument
- UNIVERSITY OF PITTSBURG Pittsburg, Etats Unis
- INSTITUT DE BIOLOGIE DU DEVELOPEMENT DE MARSEILLE LUMINY Marseille,France
- FACULTÉ DE MÉDECINE Clermont-Ferrand ,France
- INSTITUT DE MYOLOGIE, HOPITAL PITIE SALPETRIERE Paris,France
- INSERM INSTITUT COCHIN Paris,France
- FACULTE DE MEDECINE St Etienne,France
- INSERM, UNIVERSITE DE MONTPELLIER Montpellier,France
- UNIVERSTITE DE FRANCHE COMPTE Besancon,France
- GENETHON Evry,France
- INSERM,HOPITAL ROBERT DEBRE Paris, France
- CNRS UNIVERSITE CLAUDE BERNARD Villeurbanne, France
- EA 3544, UNIVERSITE PARIS SUD Châtenay Malabry, France
- CNRS UMR 7102, UPMC Paris, France
- INSTITUT DE RECHERCHE PIERRE FABRE Castres,France
- UNIVERSITE DE LAUSANNE, DPT ANESTHESIOLOGIE Lausanne,Suisse
- ECOLE VETERINAIRE, PHARMACOLOGIE Nantes,France
- Behavioral Effects of Fluoxetine in an Animal Model of Anxiety/Depression Are Mediated by Both Neurogenesis-Dependent and -Independent Mechanisms, by DJ. David, BA. Samuels, Q. Rainer, JW. Wang et al., in Neuron, 62, 2009
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Bioseb has developped a really simple to use and miniature actimetry system, including exhaustive functions to quantify rodent activity, with a very competitive pricing for your short and long term experiments and phenotyping on mouse and rat. The ActiV-Meter actimetry activity measurement system allows the assessment of the rodent's activity in its familiar environment in the Home Cage, and it can also be used in any other kind of environment (open field, etc ...)
How does it work?
Very different from other techniques, our new actimeter "ActiV-Meter" does not require any kind of surgical implantation on the animal (mouse or rat), does not involve any kind of modification to the home cage, and is not disturbed by any change (like litter movements) in the cage environment. Unlike other actimeter systems like the Infra-red beams and the video image analysis monitoring, which are really not usable with litter, not very accurate in spatial definition and which cannot detect small movements and subtle behaviors as for example the “tremor”, the ActiV-Meter is using an actimetry technique close to the force based actometers, but does not imply the use of specific cages and algorithms which make them very expensive to set up and use on a day to day practice.
Benefits
The originality of the ActiV-Meter from Bioseb lies in its ability to quantify 3 parameters of animal behaviour: Movement / Motionless Activity (including tremor) / Immobility.
Among other advantages, this actimeter is characterized by its ease of use, the fact that the activity measurement can take place in the Home Cage as well as in Open Field, and that the animal, mouse or rat, is unrestrained during the experience. Using food and a bottle, activity measurement experiences can be conducted on a very long span of time.
The operator can define his own immobility standard as well as the thresholds between slow motion and fast motion. During the actimetry experience, the operator can see on the screen the real time activity type, the position and motion and the parameters measured during each sampling period for each animal (mouse or rat). The operator can also marks special behaviours using a notepad and keyboard shortcuts. Raw acquisition data files are stored in a proprietary format to meet GLP standards, while a .txt version can be used for further activity analysis.
All of this at a fraction of the usual price of other actimeter systems and with a much easier setup.
Measured Parameters
Results can be used directly in MS Excel or in .txt format - measured parameters are:
- Immobility time (for example during sleeping), defined with a threshold,
- Motionless activity duration (for example while the animal is eating or scratching)
- Animal movement: distance (meters) and duration, possibility to distinguish between slow motion and fast motion
- Rearing can be detected with an optional equipment especially useful when wrkin in an open field
- Important notice: the actimeter system is able to measure movements while the animal is hanging under the grid covering the cage, which is a normal behaviour especially by mice.
BIO-ACTIV Software for actimetry data acquisition and data replay
!New! Publication:
Bioseb team presents its respectful thanks to research teams of Prof. David (Université Paris-Sud) and Prof. Samuels (Columbia University, New York), who used the Activ_Meter (Actimeter for Rodents) during their recent studies:
Behavioral Effects of Fluoxetine in an Animal Model of Anxiety/Depression Are Mediated by Both Neurogenesis-Dependent and -Independent Mechanisms, by DJ. David, BA. Samuels, Q. Rainer, JW. Wang et al., in Neuron, 62, 2009
(Click here to download this article as a PDF file)
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THE INFORMATION IN THIS WEB SITE AND IN LINKED PAGES AND DOCUMENTS IS PROVIDED "AS IS" AND DOES NOT CREATE ANY EXPRESS OR IMPLIED WARRANTY ABOUT BIOSEB OR ITS PRODUCTS OR SERVICES.
Information published on this Web Site as well as services, product specifications, availability and prices are subject to change without notice. BIOSEB may also make improvements and/or changes in the products and/or the programs described in this Web Site at any time without notice.
BIOSEB has made reasonable efforts to verify that the information in this Web site was accurate when first published. Such information may contain errors or omissions, however, and it is subject to change without notice. Bioseb does not undertake to update this information to include any such changes or to correct errors or omissions. Bioseb assumes no responsibility for any use of the information in this Web site or for any infringement of patents or other rights of third parties that may result. Certain information may be country-specific and may not apply in all countries.
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Overall Dimensions (Lx W x H cm) |
23 x 14 x 5, 1950 g
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Power supply |
from PC USB port
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Number of ActiV-Meters per PC |
Up to 8
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Sensor calibration / accuracy |
User calibration
Aampling rate 100/300Hz
Spatial accuracy : better than 0,8 cm
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ActiV Meter for Mice |
Recommended Home cage : Eurocage Type II
Max. weight cages up to 2 000g for animals heavier than 17g
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ActiV Meter for Rats |
Recommended Home cage : Eurocage Type II
Max. weight cages up to 4 000g for animals of less than 500g.
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Delivered with |
Software BIO-ACTIV to monitor up to 8 different cages simultaneously, mouse management and data management included, Raw datas with sampling rate 100/300Hz, encrypted (glp) averaged and recorded results directly exported in xls or txt files, complete file describing the animal position and behavior status, user defined timing of data presentation from 1 second to days, Replay and control: at any time, remotly, all experiments can be re-analysed at user will, analysis of animal – groups , and results gathered by protocols…..
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PC Requirement for software |
2GO RAM, Fast processor, Windows XP/Vista , USB port
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Option |
Rearing accessories and cages Home cage, Open field, mazes, behavior experiment cages.
Contact Bioseb for more information. |
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Model:
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ACTIV-METER-M
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ActiV_Meter: Bioseb's Actimeter for Mice
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For Mice |
Contact us
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Accessories :
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Bioseb
Tél :+33 (0)820 825 523 Fax :+33 (0)820 825 521
E-Mail : info@bioseb.com
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