INSERM GENOPOLE EVRY (France) UCB PHARMA BRUSSELS (Belgium) KEYOBS ORLEANS (France) CNRS BORDEAUX (Fr) PIERRE FABRE TOURS (Fr) CNRS NANCY (Fr) INSERM MEDICAL SCHOOL ROUEN (Fr) ICS ILKIRCH INSERM PHARMACY SCHOOL ILKIRCH (Fr) UNIVERSITY RENNES (Fr) INSERM LILLE (Fr) INSERM PHARMACY SCHOOL LYON (Fr) CRESSA GRENOBLE (Fr) GENEVA UNIVERSITY (SWITZERLAND) INSERM NEUREVA MONTPELLIER (Fr) UNIVERSITY AMIENS (Fr)
Exploratory activity and motor coordination in old versus middle-aged C57BL/6J mice. By R.Lalonde & C.Strazielle. In Archive Geront. & Ger., November 2008.
Effects of a B-vitamin-deficient diet on exploratory activity, motor coordination, and spatial learning in youg adult Balb/c mice. By R.Lalonde, H.Barraud, J.Ravey, JL.Guéant & al. In Brain Research, Vol 1188 p.122, January 2008.
Relations between open-field, elevated plus-maze, and emergence test as display by C57/BL6J and BZLB/c mice. By R.Lalonde, C.Strazielle. In The Journal of Neuroscience Methods, V171. June 2008.
PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus. By B.Reddy Vennaa, D.Deplanquea, C.Alletb, K.Belarbib & al. In Psychoneuroendocrinology 199-211. 2008 Oct 10.
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturances. By GB.Bantsielea, D.Bentué-Ferrera, S.Saïkalib, B.Laviollec & al. In Behavioural Brain Research265-71. 2009 Mar 3.
Exploratory activity and motor coordination in old versus middle-aged C57BL/6J mice. By R.Lalonde & C.Straziellec. In Arch Gerontol Geriatr Journal39-42. In 2009 Jul-Aug.
Association of caffeine to MDMA does not increase antinociception by potentiates adverse effects of this recreational drug, by Camarasa J et al. ,in Brain Res. 1111:72-82. 2005(mouse, Spain)
Chipana C et al. (2006), Protection against NMDA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: Involvement of nicotinic receptors, in Neuropharmacol. 51:885-895. (Mouse, Spain)
Methyllycaconitine Prevents Methamphetamine-Induced Effects in Mouse Striatum: Involvement of Nicotinic Receptors, by Escubedo E et al., in J. Pharmacol. Exp. Ther. 315:658-667. 2005(mouse, Spain).
Androgen Receptor Null Male Mice Develop Late-Onset Obesity Caused by Decreased Energy Expenditure and Lipolytic Activity but Show Normal Insulin Sensitivity With High Adiponectin Secretion,by Fan W et al., in Diabetes 54:1000-1008. 2005(Mouse, Japan)
Generation and characterization of Rgs4 mutant mice,by Grillet N et al., in Mol. Cell. Biol. 25(10) 4221-4228. 2005(mouse, France)
Ethopharmacological approaches used in developmental neurotoxicology,by Kovacovscky P et al., in Biologia 60/suppl17: 41-44. 2005(rat, Slovakia).
Effects of riluzole on combined MPTP + 3-nitropropionic acid-induced mild to moderate striatonigral degeneration in mice,by Diguet et al, in Journal of Neural Transmission, Volume 112, Number 5, May 2005 (mouse, France)
CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors, by Babovic et al, in Neuropsychopharmacology. 2005 Feb;30(2):339-49. (mouse, France)
Our Infra Red beams ACTIMETER shows some unique features as:
• A complete microelectonic controled and stand alone equipment to measure free surface movements (x,y) and rearing behaviour (z dimension) on mouse or rat,
• In using 1 sensors frame, the system can also be configured as a “hole board”
• RS232 PC link for data transfert (free SEDACOM software),
A powerful optional tracking system with 0,2 second time resolution and 1,25 cm distance resolution. This ACTITRACK option allows in depth analysis of rodent displacements and behaviour, using zoning possibilities, circadian, rotations, sygmo tactyl behaviour …
• 32 Actimeters, including surface + rearing frames, can be linked and recorded together, without any interface board addition to the pc.
• Each Actimeter allows the monitoring of 1 animal, or of 2 mice when using the ACTITRACK option
You will find more details on the LE-8811 Infra Red Actimeter system in the .pdf file enclosed
LE-8810 Actimeter includes the following items:
• 2 x squared frames LE-8816 with 22x22cm of internal space, each including 16 IR beam cells on each side (x ans y axis)
• 1 LE-8818 to support the 2 frames
• 1 electronic data logger and control unit (LE-8825) allowing the monitoring of 1 or 2 of the above frames. The large lcd display allows to set up the protocols (test duration, sampling time of data acquisition, animal activity threshold …), and to read the results of the activity, either “global”, surface or rearing, slow and fast movements, stereotypic moves, number of rearings…. A last set up allows using the LE-8810 as a “hole board”.
• It is worth to remember that each individual sensors frame can be set as a “surface (x,y) actimeter”, or as a “rearing actimeter”. Thus allowing one LE-8810 system to monitor 1 animal in the 3 dimensions (x,y,z) or 2 animals in (x,y) dimensions.
• SEDACOM software for Microsoft Windows and the RS232 cables are also included
Options:
• LE-8813 transparent perpex arena (open field 44x44 cm)
• LE-8824 Hole poke base for the Hole board set up.
• LE-8823 Divider to monitor 2 animal in the LE-8813 arena
ACTITRACK Software for up to 32 frames (ie up to 64 animals) via the RS232 port of a PC
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