INSERM FACULTE DE MEDECINE Paris & Clermont-Ferrand, France
MEDIMMUNE Cambridge, Royaume Unis
UNIVERSITY OF WASHINGTON Seattle, Etats-Unis
FACULTY MEDICINE OF PORTO Porto, Portugal
CHU PELLEGRIN Bordeaux, France
UNIL Lausanne, Suisse
HOWARD FLOREY INSTITUTE Carlton, Australie
TROPHOS SA Marseille, France
CNRS Valbonne, France
CHU DE NICE Nice, France
ABBOTT Louvain la neuve, Belgique
UNIVERSTITE PARIS 7 Paris, France
ANS BIOTECH St Beauzire, France
CENTRE HOSPITALIER ESQUIROL Limoges, France
LABORATOIRES PIERRE FABRE CASTRES, France
SANOFI AVENTIS Vitry sur Seine, Toulouse, Rueil Malmaison, Bagneux, Paris, Montpellier, France
ESCPI Paris, France
IGBMC PARC INNOVATION ILLKIRCH, France
PORSOLT AND PARTNERS Boulogne, France
AND MANY OTHERS SINCE 1999...
Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent peripheral local inflammation. By Benani A et al. In European Journal Neuroscience, 18: 1904-1914, 2003.
Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers. By Chassaing C et al. In British Journal of Clinical Pharmacology, 61(4): 389, 2006.
Acetaminophen reinforces descending inhibitory pain pathways. By Pickering G et al. In The Journal of Clinical Pharmacology, 84(1):47-51, 2007.
Antinociceptive and anti-allodynic effects of oral PL37, a complete inhibitor of enkephalin-catabolizing enzymes, in a rat model of peripheral neuropathic pain induced by vincristine. By Thibault K et al. In European Journal Pharmacology , 600(1-3):71-77, 2008.
Cutaneous Amitriptyline in Human Volunteers: Differential Effects on the Components of Sensory Information. Anesthesiology. By Duale C et al. In Anesthesiology 108(4):714-721, 2008.
Motor cortex rTMS in chronic neuropathic pain: pain relief is associated with thermal sensory perception improvement. By JP.Lefaucheur, X.Drouot, I.Menard-Lefaucheur & al. In Journal of Neurology, Neurosurgery, & Psychiatry, British Medical Journal, Jan 2008
Involvement of the Basal cholinergic forebrain in the mediation of general (Propofol) anesthesia. By FZ.Laalou, AP de Vasconcelos, P.Oberling & al. In Anesthesiology, Vol 108, No5, p.888-896. 2008.
Immediate electrical stimulation enhance regeneration and reinnervation and modulates spinal plastic changes after sciatic nerve injury and repair. By M.Vivo, A.Puigdemasa, L.Casals, E.Asenio & al. In Experimental neurology , Vol 211, Issue 1, p.180-193. May 2008
Nefopam and ketoprofen synergy in rodent models of anticiception. By P.Girard, D.Verniers, MC.Coppé, Y.Pansart & al. In European Journal of Pharmacology, Vol 584, Issue 2-3, p.263-271. April 2008.
Electrical stimulation combined with exercise increase axonal regeneration after peripheral nerve injury . By E.Asensio-Pinilla, J.Jaramilloa & X.Navarro. In Experimental Neurology 258-65. 2009 Jun 3.
Nociceptive responses & spinal plastic changes of afferent C-fibers in three neuropathic models induced by sciatic nerve injury in the rat. By L.Casals-Diaz; M.Vivo & X.Navarro. In Experimental Neurology 84-95. 2009 Feb 3.
The new Electronic Von Frey unit EVF3 is easy to use and allows you to quickly find the sensitivity threshold in rodents.
This value is measured in only ONE test, and is highly repetitive. With the same analgesia equipment you will be able to carry on animal and human studies (clinical studies: only for research protocols while the agreement for Medical CE mark is in process). The resolution of the screen is 0,1 gram.
Sensibility thresold result is displayed on a large backlighted screen and you will not get any temperature or hygrometry drift as that was the case with the filaments. The Electronic Von Frey EVF3 is supplied with a COFRAC related calibration certificate (ISO 9000), and an EMC conformity agreement.
Main functionalities:
• Large backlighted LCD screen displaying current and peak value
• Statistical functions: average value and standard deviation are computed for each subject
• Stand-alone instrument: internal memory allows the storing of up to 100 values, which may be transfered to a PC using our optional software
A few options for easier operations:
• A patient switch allows to freeze the displayed value when
the threshold is reached
• An RS232 interface allows to transfer the displayed value
on to a computer
• Our RSIC software allows to write directly on EXCEL7 the
value measured (PC with Windows 98 or XP) thus you avoid
transcription errors, and get instant report
Supplied with:
• 1 calibration certificate (yearly re-calibration carried out by BIOSEB)
• 1 EMC agreement
• 10 disposable plastic tips
• 1 spring tip for thresholds between 0 and 10 gramms
• Footswitch to reset the display to zero
• Carrying case for transport
THE INFORMATION IN THIS WEB SITE AND IN LINKED PAGES AND DOCUMENTS IS PROVIDED "AS IS" AND DOES NOT CREATE ANY EXPRESS OR IMPLIED WARRANTY ABOUT BIOSEB OR ITS PRODUCTS OR SERVICES.
Information published on this Web Site as well as services, product specifications, availability and prices are subject to change without notice. BIOSEB may also make improvements and/or changes in the products and/or the programs described in this Web Site at any time without notice.
BIOSEB has made reasonable efforts to verify that the information in this Web site was accurate when first published. Such information may contain errors or omissions, however, and it is subject to change without notice. Bioseb does not undertake to update this information to include any such changes or to correct errors or omissions. Bioseb assumes no responsibility for any use of the information in this Web site or for any infringement of patents or other rights of third parties that may result. Certain information may be country-specific and may not apply in all countries.
Measurement range
0 to 500 grams (5N)
Resolution
0,1gram
Accuracy
0,2 gram
Overload
120 % without causing any damage to the sensor
Temperature Compensation
from 0 to 50°C.
Display
Extra Large and easy to read multilines - backlighted LCD PEAK value and CURRENT value on the same screen Bargraph of capacity Result: sensitivity threshold = max value
Statistical functions
Average value and standard deviation are computed for each subject
Show images gallery
The new Electronic Von Frey unit EVF3 is easy to use and allows you to quickly find the sensitivity threshold in rodents.
Main functionalities:
