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ANALGESIA
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Cold Hot Plate Test
Click here to maximize 		Cold Hot Plate Test

For testing animal's sensitivity to pain resulting from exposure to heat or cold: the Cold Hot Plate is an innovative instrument opening new investigation fields for your analgesia research.

- Users - Publications - Technical specifications - Others products / accessories -
 
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    The Bioseb Cold and Hot Plate Analgesia Meter is based on a metal plate which can be heated to 65°C and cooled to -3°C (with an ambient temperature between 20°C and 25°C). An electronic thermostat maintains the plate's temperature and a front panel digital thermometer displays the current plate temperature.

    Operation Principle
    The animal's pain sensitivity resulting from exposure to heat or cold is tested by placing the animal (mouse or rat) on the surface of the plate and starting a built-in timer. The operator stops the timer at the instant the animal lifts its paw from the plate, reacting to the discomfort. The front panel timer then displays the number of seconds it took the animal to react. Animal reaction time is a measurement of animal resistance to pain and is used to measure efficacy of analgesics.

    The Bioseb Cold and Hot Plate is designed to be very simple to use at very fast to reach the set temperature (as example From ambient to 4°C, the most used threhold value, it takes less than 10 minutes, and from 4°C to 65°C it takes only 5 minutes) . Metrology wise, is accurate to less than 0,5°C (EEC metrology standard) and perfectly constant in the animal holder system. The preset température will not change for more than 0,1°C when a 400g rat is placed on the plate, and return to the set temperature is almost immediate.

    The operator can start and stop the timer with the front panel start/stop switch or with the included footswitch, which allows "hands-free" operation.

    The Cold Hot Plate Test Analgesia Meter can be complemented by a software allowing for temperature "ramps" and “loops”, predefined by the user. This feature is mainly used for studies with telemetry implants. In addition to displaying the reaction time, the Cold/Hot Plate Analgesia Meter is able to send the same information via USB interface to a computer.

    !New! Publication

    Bioseb team presents its respectful thanks to research team of Prof. Poisbeau (Institut des Neurosciences Cellulaires et Intégratives de Strasbourg), who used the Cold and Hot Plate Test during its recent studies:

    Differentiating Thermal Allodynia and Hyperalgesia Using Dynamic Hot and Cold Plate in Rodents, by I. Yalcin, A. Charlet, MJ. Freund-Mercier, M. Barrot and P. Poisbeau, in The Journal of Pain, 2009
    (Click here to download this article as a PDF file)

    Description may be subject to change in further versions

Technical specifications (Click here to see our "Information Liability Disclaimer")

Temp range -3 degrees C. to 65 degrees C (in 20 to 25 degree C. ambient environment, 50% RH)
Temp accuracy +/- 0.5 degrees C.
Temperature uniformity on plate +/- 0.5 degrees C.
Power requirements 110V/220V automatic, 100W
Plate Dimensions 165 x 165 mm
Control unit dimensions 305 x 280 x 158 mm
Weight 6,650 kg

Model:
BIO-CHP
Cold Hot Plate Test
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Linked products:
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Thermal Place Preference, 2 Temperatures Choice Nociception Test
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BIO-TGT2
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LE-7406
Hot Plate Test
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Print version Handbook
(PDF format)
Instrument's tutorial
Instrument's FAQ
 Demonstration
video 		Click to order

Bioseb

Tél :+33 (0)820 825 523
Fax :+33 (0)820 825 521
E-Mail :info@bioseb.com

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