The Digital Water Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances.

Operating principle
Basically, the volume transducer is formed by two Perspex tubes interconnected and filled with a conductive solution and a platinum electrode for each chamber. All the system is supported by a stand (included) that can be placed over the control unit.

The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes. The Plethysmometer Control Unit detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured (0.01 ml resolution). The current value remains in the digital display until a new trial starts. The Control Unit is automatically zeroed between successive readings, thus making intermediate adjustments unnecessary.

The system includes as standard a volume transducer with its related calibrator and a 100 ml solution. A remote foot-switch allowing rapid hands-free experiments can be used to set control the end point of the measurement. SeDaCom software supplied with the unit can be used to automatically record the results on a PC through a RS 232 port.

Parameters Measured
• Mice paw volume (ml)
• Rat paw volume (ml)

Key features
• Computer interface
• Foot-switch control
• Automatic zero adjustment

Components included
• Control Unit with RS232 communication port to PC
• Pedal Switch
• Stimulation Unit
• 1ml, 3ml or 5ml cell with electrode
• 1ml or 3ml volume gauge
• SeDaCom Software
• Instructions manual
• Certificate of calibration
• Cables, connectors
• 2 years warranty
• Set of two spare fuses

Options
• LE7000 Thermal printer