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Plethysmometer
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Plethysmometer

Follow the evolution of the inflammatory response experimentally induced in rodents and screen potential anti-inflammatory or anti-oedema properties of pharmacological substances
 
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    The Digital Water Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances.

    Operating principle
    Basically, the volume transducer is formed by two Perspex tubes interconnected and filled with a conductive solution and a platinum electrode for each chamber. All the system is supported by a stand (included) that can be placed over the control unit.

    The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes. The Plethysmometer Control Unit detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured (0.01 ml resolution). The current value remains in the digital display until a new trial starts. The Control Unit is automatically zeroed between successive readings, thus making intermediate adjustments unnecessary.

    The system includes as standard a volume transducer with its related calibrator and a 100 ml solution. A remote foot-switch allowing rapid hands-free experiments can be used to set control the end point of the measurement. SeDaCom software supplied with the unit can be used to automatically record the results on a PC through a RS 232 port.

    Parameters Measured
    • Mice paw volume (ml)
    • Rat paw volume (ml)

    Key features
    • Computer interface
    • Foot-switch control
    • Automatic zero adjustment

    Components included
    • Control Unit with RS232 communication port to PC
    • Pedal Switch
    • Stimulation Unit
    • 1ml, 3ml or 5ml cell with electrode
    • 1ml or 3ml volume gauge
    • SeDaCom Software
    • Instructions manual
    • Certificate of calibration
    • Cables, connectors
    • 2 years warranty
    • Set of two spare fuses

    Options
    • LE7000 Thermal printer


Control Unit Dimensions 280 (W) x 280 (D) x 110 (H)
Stimulation Unit Dimensions 230 (W) x 220 (D) x 300 (H)
Power Supply 220V/110V, 50/60Hz
Starting By panel key or pedal switch
Resolution 3 digits, 0,01 steps
Computer Requirements PC (Windows 95, 98, ME, NT, 2000 and XP)
Material Composition Clear methacrylate (cell), satinless steel (stand), platinum (electrode)
Maximum number of stations 1 per computer (multiple set-ups also available under request)
Certifications CE Compliant

Model:
LE-7500
Plethysmometer
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Accessories :
LE-7504
1 ml cell with electrode
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LE-7503
3 ml cell with electrode
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LE-7505
5 ml cell with electrode
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LE-7506
Platinum electrode
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LE-7000
Thermal Printer
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Print version Handbook
(PDF format)
Instrument's tutorial
Instrument's FAQ
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