! NEW RESEARCH WORK !
A recent publication
by E. Cobos, N. Ghasemlou, D. Araldi, D. Segal, K. Duong et al. in "Pain" highlights the merits of using Bioseb's Plethysmometer
: Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia.
The Digital Water Plethysmometer
is designed to provide a highly useful tool in the measurement of small volume changes.
This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances.
Basically, the volume transducer is formed by two Perspex tubes interconnected and filled with a conductive solution and a platinum electrode for each chamber. All the system is supported by a stand (included) that can be placed over the control unit.
The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes.
The Plethysmometer Control Unit
detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured (0.01 ml resolution). The current value remains in the digital display until a new trial starts. The Control Unit is automatically zeroed between successive readings, thus making intermediate adjustments unnecessary.
A remote foot-switch allowing rapid hands-free experiments can be used to set control the end point of the measurement.
The optional SEDACOM software
(new version 2.0 available) can be used and represents an easy and convenient way to visualize and export the data on a computer for further analysis.
• Mice paw volume (ml)
• Rat paw volume (ml)
• Computer interface
• Foot-switch control
• Automatic zero adjustment
• Control Unit with RS232 communication port to PC
• Pedal Switch
• Stimulation Unit
• 1ml, 3ml or 5ml cell with electrode
• 1ml or 3ml volume gauge
• SeDaCom Software
• Instructions manual
• Certificate of calibration
• Cables, connectors
• 2 years warranty
• Set of two spare fuses
• LE7000 Thermal printer