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ANALGESIA
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Hot Plate Test
Click here to maximize 		Hot Plate Test

for evaluating thermal analgesia or hyperalgesia in rodents

- Technical specifications -
 
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    The LE7406 Hot-Plate performs rapid and precise screening of analgesic drug properties on small-laboratory animals according to the ‘hot-plate test’. The animal’s pain sensitivity alterations induced by a specific experimental context change and/or genetic manipulations can also be evaluated through this method.

    Basically, the hot-plate test, initially described by N.B. Eddy and D. Leimbach (1953), evaluates thermal pain reflexes due to footpad contact with a heated surface. During the experiments, the animal is confined in a removable clear acrylic cylinder where the latency time to the first hind paw or/and jumping responses are measured.

    In the LE7406 Hot-Plate, a thick aluminium plate (10 mm) provides a high temperature stability and even surface distribution. The plate temperature can be held at a set point between 45 and 62°C (± 0.1ºC) by multiple proportional feedback circuits that minimize overshoot. A built-in timer activated by an external foot switch allows precise measurement of reaction time (0.1 sec precision). A remote foot-switch controls the test start/stop allowing rapid hands-free experiments. The operator can read the animal reaction time from the display or from a PC computer using the SeDaCom software. Trial number, plate temperature and reaction time are then sent to the PC through a RS 232 port.

Technical specifications (Click here to see our "Information Liability Disclaimer")

Base Dimensions 200 (W) x 300 (D) x 110 (H) mm
Plate Dimensions 200 (D) mm
Cylinder Dimensions 200 (D) x 250 (H) mm
Operating Temperature 45 to 62 degrees Celsius - 0,1 steps
Reaction time 3 digits, 0,01 secs. increment
Material Composition Clear methacrylate (animal holder), aluminium (plate)
Computer requirements PC (Windows 95, 98, ME, NT, 2000 and XP)
Maximum number of stations 1 per computer (multiple set-ups also available under request)
Power Requirements 110V or 220V, 50/60Hz
Certifications CE Compliant

Model:
LE-7406
Hot Plate Test
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