! NEW RESEARCH WORK !
A recent publication
by KW Chiu, J Hash, R Meyers, BDX Lascelles in "Scientific Reports" highlights the merits of using Bioseb's Vetalgo: Algometer for Big Mammals
: The effect of spontaneous osteoarthritis on conditioned pain modulation in the canine model
Bioseb's new Algometer
for Big Mammals
3 different stimulator probes
Bioseb’s Vetalgo, or Algometer for Big Mammals, is a new pressure-based analgesimeter especially designed for big mammals
. Delivered with a set of 3 different-size stimulators, the profile of mechanical stimulus and the application surface can be adapted to various animal’s size (horses, cats, dogs, pigs, sheep, calves
) and to various testing sites : joints, vertebras, pelvic area, hoof, wound, soft tissue, muscle, horn, metatarsus, carpal pad etc.
Von Frey filaments are commonly used to quantify pain or to assess sensitivity, but this technique is time-consuming and does not avoid cross-contamination - moreover, it is limited to 300g of force. The full capacity of our Pressure Algometer being 5000g (ie. 50N), the device allows pain threshold measurement for most big mammals.
Veterinary studies, such as “Briley, J.D., et al. Feasibility and repeatability of cold and mechanical quantitative sensory testing in normal dogs. The Veterinary Journal (2013)
, “show the importance of quantitative sensory testing (QST) to evaluate pain threshold in mammals with OA inflammation, pelvic pain or muscle-related troubles.
The repeatability and the validity of Bioseb’s "Vetalgo" Pressure Algometer
have been demonstrated, and is now recommended as part of a multimodal and complete somatosensory evaluation set
. It is a must on veterinary’s standard equipment for the improvement of Animal’s life quality.
Bioseb’s "Vetalgo" Pressure Algometer for big mammals is simple to operate : a Force-gauge display is equipped to an external stimulator. The assembly is mounted on an ergonomic handle, that fits both left-handed and right-handed investigators. The type of stimulator is to be chosen according to the application surface and the type of nociceptive stimulus to be applied.
After placing the animal on a safe position, a progressive force is applied by the investigator on the area of interest. The increasing stimulus is applied until a response from the animal is noticed, for example deliberate escape movement away from the device, vocalization, attempts to bite or to scratch the instrument, turning the look at the testing site, etc.
Both maximum and current MNT (Mechanical Nociceptive Threshold)
values are shown on real-time on the large led screen of the display. The MNT value correspond the value at which the animal reacts, being the Max. value of Pressure application, in the standard steadily increasing procedure.
The measurement is accomplished using a highly accurate sensor of 5000g Max. Capacity and an electronic device offering a sampling rate of 1000 Hz. This ensures that the maximum force is perfectly captured and displayed, even for short and low force peaks – this allowing test of a wide range of animal’s pain sensitivity.
Measurements can be recorder and displayed in grams, Newtons, or lbs. The unit is directly selected on the keyboard. Data output is available through a RS232 port, a printer, or a graphic recorder. Individual measurements (up to 100) are stored in an internal memory, and can be downloaded after the experiment.
• Objective and immediate reading of Mechanical Nociceptive Threshold (MNT)
• Mechanical stimulus up to 50 N
• Certified repeatable and reliable values over time
• Single instrument for a wide animal range : interchangeable tips to fit to a wide range of animal’s size
• 3 stimulators, profiled for various mechanical stimulus type
• Wire-less device, works on rechargeable batteries
• Reduced size and ergonomic handle (fits left-handed and right-handed operators)
• Robust design for use in animal housing
• Delivered with disposable plastic tips and cleanable steel tips, no cross-contamination
Domains of application|
• Veterinary Medicine, Animal Welfare and Pain Release
• Part of a complete somatosensory testing, for all big mammals
• Prior to surgery : Adjustment of anesthetic methods to the animal's sensitivity level
• Post-operative pain and wound sensitivity, ie ovariohysterectomy
• Rehabilitation practice: daily use as objective Pain release Evaluation
• Drug screening, especially Analgesics efficacy for Post-surgery and Anesthetics
• Chronic Pain, Osteoarthritis, rheumatoid Arthritis
• Musculoskeletal sensitivity, Orthopedic dysfunctions, ie. cruciate ligament rupture
• Abdominal Ventral , Pelvic, Visceral pain
BIO-CIS Software for our Algometer
An embedded statistical computation has been included in the electronic device. This is a very useful feature that has been very well received by researchers, especially when a large number of tests is required. The display shows in real time the mean, standard deviation and variation coefficient from groups of animals.
The optional BIO-CIS software sends data acquired via the Pressure Algometer into an MS Excel spreadsheet using the RS232 port and USB converter. Easy to set up, this software interface also allows the display of the applied force vs. time for different trials, which is a useful function for the technician training (repeatability improvement).
• 1 Force-gauge display
• 1 handle
• 3 stimulator tips
• 1 power adaptor (110-220 V)
• User Manual
• Delivered in its smart suitcase