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ALGOKIT ANALGESIMETER
(Model: BIO-ALGOKIT)
An economical and versatile solution for when flexible quantitative sensory testing (QST) is needed: built around our Static Weight Bearing test and its state-of-the-art colour, touchscreen console, the Algokit can include up to 3 additional sensors among our Electronic Von Frey, Rodent Pincher and Small Animal Algometer (SMALGO). With a common control unit and software, it offers a convenient, compact benchtop footprint.

A perfect solution for all your research on analgesia, nociception, inflammation, neuro-pathologies and post-operative pain.


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Technical specifications  
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Presentation


In order to offer an answer to all your requests regarding different situations of pain measurement, Bioseb is proud to present an innovative, complete solution built around our Static Weight Bearing Test and combining up to 3 sensors amoung our Electronic Von Frey, Rodent Pincher and Small animal Algometer, all connected to one unique Control Unit.

Operating principles

Each of our pain threshold measurement instruments is based on a dedicated configuration which is originally stored in the associated console unit. We upgraded our system to save the configuration directly in the sensor devices, which now allows us to use several instruments with one single interface: the Static Weight Bearing Test and its touchscreen, colour console. The "Plug and Play" principle lets you simply switch off the console unit, change the sensor and resume your work.

This AlgoKit solution can be combined with our BIO-CIS software to improve the repeatability of reflex nociceptive tests. Stimulated pain resistance tests are well known to be highly operator-dependent. BIO-CIS, by displaying in real time the force vs time, greatly helps the operator to improve their skills with the instrument and generate an impactful graphic representation of the data.

Features:

• Flexible instrument when a quantitative sensory testing (QST) is needed
• Compatible with our BIO-CIS software to improve repeatability in nociceptive testing
• Control unit features a large backlit display
• Statistical functions: mean and standard deviation values for each animal
• Internal memory with up to 100 values
• Runs on battery for more flexibility
Static Weight Bearing Test by Bioseb
Static Weight Bearing Test

The Core of the AlgoKit: our Static Weight Bearing Test

An easy and non pain-inducing solution for assessing the level of discomfort (incapacitance) in the injured paw of a small animal like a rat or a mouse by measuring the Postural Equilibrium – independently of the operator. The static weight bearing instrument is ideal for your research on analagesia and nociception involving rodents: osteo arthrisis, cartilage degeneration, inflammation models, nerve injury models, and much more... Discover the SWB-Touch: now with a brand new touch-screen console!

By continuously measuring the weight borne by each paw, Bioseb's Static Weight Bearing Incapacitance Test allows the objective measurement of spontaneous pain by assessing the postural equilibrium, thus opening research fields not available when using traditional methods (like the Randall & Selitto test), which can only measure nociceptive thresholds and pain sensitivity using experimental nociceptive stimuli.

Available sensors

Electronic Von Frey
Presentation
A quick solution to determine the mechanical sensitivity threshold in rodents (mice and rats). This precise and easy-to-use electronic instrument is a must-have reference for your research in analgesia, nociception, neuro-pathologies and post-operative pain.

Stimulation
Stimulation is usually applied on the rodent's hind paws. The paw's withdrawal following the mechanical stimulation is recorded as a response to the stimulus.

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Pincher
Presentation
A fast and accurate algometer based on an instrumented pincher, allowing accurate nociceptive tests to measure mechanical pain threshold on rat or mouse limbs with minimal constraint.

Stimulation
The pressure is applied in the "inter-digital" region, but can also be applied to the tail for rats. The instrument displays the force at which the animal reacts and reports the nociception threshold.

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SMALGO
Presentation
Dedicated to small animals, like mice and rats, Smalgo is a pressure-based analgesimeter designed for easy assessment of sensitivity threshold. It is a must for osteo-arthritis and pain studies.

Stimulation
The operator adjusts the algometer to the thumb and applies a progressive pressure to the relevant location on the animal (usually joints or back), as if he was applying the pressure directly with his own finger.

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Dedicated BIO-CIS Software

Dedicated BIO-CIS Software to increase nociceptive tests repeatability
Dedicated BIO-CIS Software
The multi-instrument BIO-CIS Software, by Bioseb, is compatible with all our mechanical allodynia / nociception measurement instruments and allows you to reduce inter-operator variability, which is an issue for these kinds of tests.

BIO-CIS can be used in two different ways with the Electronic Von Frey, Rodent Pincher and Smalgo:

Direct measurement: When a sensor is connected to the BIO-CIS software during stimulation, the software displays the real-time graph of applied force vs time in real-time. Additional features allows the definition of a theoretical ramp (force/time) with upper-lower limits to be followed and displayed during the measurement and curves of a group of measures can be reloaded and displayed simultaneously for a graphical overview. These options greatly help the operator to improve their skills with the instrument and reduce operator-introduced variability and is useful for generating impactful figures.

• Indirect measurement: The control unit embeds an internal memory allowing you to store up to 100 values measured during your experiments. You will then be able to connect the instrument to the BIO-CIS software and transfer all your results to an Excel spreadsheet.

Domains of application

• Analgesia
• Nociception
• Inflammation
• Neuro-pathologies
• Post-operative pain
• Quantitative Sensory Testing (QST)
THE INFORMATION IN THIS WEB SITE AND IN LINKED PAGES AND DOCUMENTS IS PROVIDED "AS IS" AND DOES NOT CREATE ANY EXPRESS OR IMPLIED WARRANTY ABOUT BIOSEB OR ITS PRODUCTS OR SERVICES.

Information published on this Web Site as well as services, product specifications, availability and prices are subject to change without notice. BIOSEB may also make improvements and/or changes in the products and/or the programs described in this Web Site at any time without notice.

BIOSEB has made reasonable efforts to verify that the information in this Web site was accurate when first published. Such information may contain errors or omissions, however, and it is subject to change without notice. Bioseb does not undertake to update this information to include any such changes or to correct errors or omissions. Bioseb assumes no responsibility for any use of the information in this Web site or for any infringement of patents or other rights of third parties that may result. Certain information may be country-specific and may not apply in all countries.

Static Weight Bearing (SWB) Measurement range: 0-2000g for Mouse or Rat
Resolution: 0, 2g
Accuracy: 0.1% of full Scale
Electronic Von Frey Measurement range: 0 to 500 grams (5N)
Resolution: 0,1gram
Accuracy: 0,2 gram
Overload: 120 % without causing any damage to the sensor
Temperature Compensation: from 0 to 50°C
Rodent pincher Measuring Range: 0 to 2000 grams
Resolution: 0,1 gram or 0,001 N
SMALGO Measuring Range: 0 to 1500 grams (15 N)
Sensitivity: 0.1 gram or 0.01 N
Tips: 3, 5 or 8 mm in Diameter (stainless steel)
Sampling speed: Automatically detect the respond to pain at 1000 Hz
Overload protection: 200%
Control unit Backlit display, internal memory of 100 values

Model:
BIO-ALGOKIT
ALGOKIT Analgesimeter
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Bioseb - In Vivo Research Instruments
Phone worldwide : +33 442 344 360 - USA/Canada : (727) 521-1808
e-Mail : Worldwide: info@bioseb.com - USA/Canada: info-us@bioseb.com