! NEW RESEARCH WORK !
A recent publication
by S Ni, Z Ling, X Wang, Y Cao, T Wu, R Deng, JL Crane et al in "Nature Communications" highlights the merits of using Bioseb's Spontaneous activity wheels
: Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
Activity wheel for rodent, by Bioseb
Our new Spontaneous Activity Wheel is an easy and cost-efficient way to quantify rodents' spontaneous activity
in their home cage environment (type IIL and III cages), and can be used for both mice and rats (two different models available).
The system allows you to record the parameters pertaining to the voluntary exercise of the animal
, which can freely decide upon its timing and intensity. Monitoring and recording typically takes place over extended periods of time (several days or weeks) in order to analyze the differences in behavior and exercising patterns induced by drugs or surgical manipulation. Though the analysis focuses on spontaneous activity, it is highly relevant for long-term studies on alterations of the circadian rhythm.
Measurements include the distance run both ways, the number of wheel turns, average/min/max speed, acceleration, total time in the wheel, and can be displayed in statistical form or sorted by time periods. Periods can be customized for facilitating further analysis.
An ideal tool for studies on Drug screening
, Phenotyping and Neuromuscular diseases.
New embedded LCD screen:
Highly reliable sensors
offering an excellent angular resolution (22°) as well as time resolution (0,1 seconds for up to 64 cages) accurately records the animal's spontaneous exercising behavior, even allowing the study of the mouse’s acceleration and power pattern.
A clever design
includes a coding disk as well as an LCD screen counter and Infrared sensors, as well as a “standard” cage construction from stainless steel and perpex ensures that the system is both durable and easy to use
and maintain in the daily laboratory operation.
A complete digital solution
based on Bioseb’s ACTIVW-SOFT software allows you to monitor up to 64 cages simultaneously via an external connection to the PC USB port (up to 5 m between cage and PC).
Dedicated software ACTIVW-SOFT
• Allow monitoring of spontaneous activity
• High angle and time resolution allows recording of acceleration pattern
• Practical and sturdy design is adapted for durable use and easy cleaning
• Software allows monitoring of up to 64 wheels simultaneously
• Cost-effective setting not requiring the presence of an operator (unlike treadmills)
• Now with an LCD display!
• Works for both rats and mice
Domains of application
• Drug screening
• Neuromuscular diseases
• Parkinson disease
• Duchenne muscular dystrophy
Our ACTIVW-SOFT software offers a complete solution to manage mice groups, allowing you to import/export and edit groups, as well as setup delayed acquisition start, and pause recording (for instance during cage cleaning). Data is recorded at 15Hz, then integrated at 1Hz, and can be re-compiled in analytical mode on an adjustable period of 1 sec up to 999 minutes.
Bioseb's dedicated ACTIVW-SOFT lets you visualize data in a convenient control panel, for each wheel, or for a group of wheels.
Bioseb's dedicated software for rodents' activity wheels allows customized settings for the data acquisition averaging periods (from 1second), the duration of recording, the latency period prior to account for Wheel movement, etc. Those settings can be defined according the user's needs.
• A data file computed per period with informations of speed, acceleration, wheel rotations...
• Total time of the animal in the wheel with break down in number of rotating occurences (using the preset latency time)
• Outputs: via txt file in Microsoft Excel format.