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OPERANT & BEHAVIOR MODULAR SYSTEM
(Model: BIO-OPERANT - for rats and mice)
An entirely modular experimental enclosure designed to conduct operant conditioning procedures (e.g. food reinforcement, DMTS, conflict tests, self-administration…) on rodents (rats and mice). A powerful tool for studies on Anxiety, Drug screening, Phenotyping Anhedonia, Drug dependence, Alcohol dependence, and much more. System can also be built for teaching applications.

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  • CEPHALON, Paris, France
  • UNIVERSITE DE LYON, France
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Presentation

A setup example<BR>for our Operant/Behavior Chambers for rats and mice
A setup example
for our Operant/Behavior Chambers
Our Modular Operant Chamber is an entirely modular experimental enclosure designed to conduct operant conditioning procedures (e.g. food reinforcement, DMTS, conflict tests, self-administration…) on rodents (rats or mice). A large variety of modules offering different possibilities for manipulation, cues and triggers is available to adapt the system to your research protocol. Advanced configuration and protocol control can be achieved using the available software. Contact us for a tailor-made solution matching your specific need!

Operating principle

The operant chamber is made in an entirely modular structure which allows complete disassembling or rearrangement to build a new space of different dimensions/components or to enable storage in the minimum space. It can be easily transformed from rat chamber to mice chamber (or vice versa) with a reduced cost.

A frontal door offers a total accessibility inside the chamber. Walls and cover can be of different material or colour, since they are totally removable.

Each chamber is associated with a Link Box which provides power to up to 8 (expandable to 16) Operant Modules (levers, lights, sound, dispensers, electrical shock...) conferring to the chambers a full autonomy.

The Cages can be equipped with a Weigh Transducer in order to record activity or freezing.

Research protocole examples

Food-motivated operant conditioning test

Progressive-ratio (PR) schedules permit studying food-motivated behavior.

These schedules require an increasing number of operant responses to obtain successive rewards within a session. For example, a typical PR 5 schedule requires five responses to produce the first reinforcer, and the response requirement is incremented by five each time a reinforcer is earned. The breaking point, defined as the highest ratio completed is a classical measure reflecting the efficacy or motivational strength of food, and is increased in response to food-deprivation or reward high palatability.
Self-administration test

Self administration is a classical model of human drug-taking behavior and consists in establishing in rodents an operant conditioning of an instrumental response (nose-poke, lever pressure) to obtain a reward, according to a fix or progressive ratio.

Self administration is a standard paradigm for studying the acute rewarding properties of drugs, the development of habitual drug-seeking behaviors, and ultimately, addiction. Moreover, this method can be used to assess the abuse potential of drugs.
Geller Seifter test

The Geller-Seifter paradigm is a conflict model in which prior food-deprived rodents have to “choose” between consuming food and avoiding the punishment associated with this consumption.

Basically, periods of responding by lever pressing to get sweetened condensed milk on a variable interval schedule are interrupted by periods where, in the presence of a signal, reward can be obtained more frequently but are accompanied by mild footshocks. Levels of punished responding are inversely proportional to the level of anxiety. Then, in this context, the shock-induced reduction of reward seeking can be reversed by administration of anxiolytics.


Parameters Measured

• Number of responses (LE 85XCT)
• Number of reinforcements (LE 85XCT)
• And many user-defined parameters (see PackWin software)


Key features

• Entirely modular system
• Easily transformed from rat to mice chamber
• Reduced number of cables
• Possibility of customization
• Up to 8 stations can be connected at once to PC through a single cable
Domains of application

• Anxiety
• Drug screening
• Phenotyping
• Anhedonia
• Drug dependence
• Alcohol dependence
• and much more...


THE INFORMATION IN THIS WEB SITE AND IN LINKED PAGES AND DOCUMENTS IS PROVIDED "AS IS" AND DOES NOT CREATE ANY EXPRESS OR IMPLIED WARRANTY ABOUT BIOSEB OR ITS PRODUCTS OR SERVICES.

Information published on this Web Site as well as services, product specifications, availability and prices are subject to change without notice. BIOSEB may also make improvements and/or changes in the products and/or the programs described in this Web Site at any time without notice.

BIOSEB has made reasonable efforts to verify that the information in this Web site was accurate when first published. Such information may contain errors or omissions, however, and it is subject to change without notice. Bioseb does not undertake to update this information to include any such changes or to correct errors or omissions. Bioseb assumes no responsibility for any use of the information in this Web site or for any infringement of patents or other rights of third parties that may result. Certain information may be country-specific and may not apply in all countries.

Base dimensions 440 (W) x 360 (D) x 35 (H) mm
Working area (mouse) 200 (W) x 200 (D) x 250 (H) mm
Working area (rat) 250 (W) x 250 (D) x 250 (H) mm
Material Composition Stainless steel, aluminium and methacrylate
Power Supply 110V/220V, 50/60Hz
Maximum number of stations (when working with PC) 8 stations connected to a PC
Connection of several units to PC No need of PC interfaces!. Direct connection through one cable!
Certifications CE Compliant

Model:
BIO-OPERANT
Operant & Behavior Modular System
for rats and mice Contact us

Related products:
PACKWIN
Packwin
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Bioseb - In Vivo Research Instruments
Phone worldwide : +33 442 344 360 - USA/Canada : (727) 521-1808
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