Rotational behaviour has proved a popular technique for screening the behavioural effects of a wide variety of lesions, drugs, and other experimental manipulations on the brain of rodents
. This test is widely carried out in experiments using animal models of Parkinson disease
with unilateral lesions in the dopaminergic nigrostriatal system.
Basically, the subject wears an adjustable harness with Velcro connected to the rotation sensor by a flexible tie. Wide ranges of harnesses are available to fit different animal sizes. The subject is then placed into a transparent container (cylinder or bowl) with a lateral support for a vertical stand.
A bi-directional rotation sensor
provides a double (right and left turns) output with adjustable regulation of pulses/turns (between 4 and 36 pulses per complete turn). Two configurations are available for rotation counting: individual counter or a multicounter.
When using a multicounter, the new SEDACOM 2.0 version
provides an easy and convenient way to visualize and export the data on a computer for further analysis.
• Number of partial and complete left and right turns
• Data given by user-defined intervals of time (Multicounter LE3806)
• Cylinder or Bowl transparent containers
• Rotation sensor with adjustable TTL output signal
• Configuring experiment duration and time intervals of counting
• Counting the number of partial and complete left and right turns
• Easily adjustable harness (new design)
• New optional Data Transfer software SEDACOM 2.0 (for Multicounter LE3806)
• Rotation Sensor and support
• Container (Bowl or Cylinder, to be indicated when placing an order)
• Animal Harness (for Rat or Mouse, to be indicated when placing an order)
• Counter (Individual or multiple, to be indicated when placing an order)
• Cables, connectors
• Instructions manual
• Hardware (2 years warranty), Software (1 year warranty)