The Contextual Kits for T2CT have been designed to enhance thermal place preference studies...
The Contextual Kits for T2CT have been designed to enhance thermal place preference studies...
An easy way to objectively quantify the muscular strength of mice and rats, and to assess the...
The BIOSEB Spontaneous Activity Wheel offers an effective solution for quantifying rodent...
The BIOSEB Spontaneous Activity Wheel is an easy way to quantify rodent voluntary activity in...
The uncomplicated way to monitor rodent activity over several days from their home cage...
These small animal treadmills are used for forced exercise training and accurate testing of...
For testing animal's thermal sensitivity to pain resulting from exposure to heat or cold: the...
An operator independent test to study pain thresholds in rodents (mouse and rat) by assessing...
New and improved! The operator-independent Thermal Gradient Test used to show favorite...
The Contextual Kits for T2CT have been designed to enhance thermal place preference studies...
The advanced version of our Dynamic Weight Bearing Test for rodents (rats and mice) allows for...
An easy and non pain-inducing solution for assessing the level of discomfort (incapacitance) in...
A unique device that provides automated measurement of weight bearing and force distribution...
Expand Your Analysis with Advanced Postural and Locomotor Calculations BIOSEB’s renowned...
A quick solution to determine the mechanical sensitivity threshold in rodents (mice and rats)....
As an electronic version of the classical Von Frey Filaments esthesiometer (or aesthesiometer),...
New ROBUST and modular cages to gently hold rodents (rats or mice) during nociceptive and...
An economical and versatile solution for when flexible quantitative sensory testing (QST) is...
Dedicated to small animals, like mice and rats, Smalgo is a pressure-based analgesimeter...
Bioseb's version 5 of the Tail Suspension Test system, based on both strain sensors and video...
NEW ! A complete (hardware + software), dedicated and automated solution for the Elevated Plus...
A unique setup for the automation of the Open Field test for rats and mice : 3D-camera based...
Open-field test - ARENA ONLY - used to evaluate of animal's basal activity and its evolution for...
The new Forced Swimming Test system from Bioseb uses a dual approach: Combining a double input...
A brand new innovative setup for the automation of the Novel Object Recognition Test : 3D-camera...
Open-field test - ARENA ONLY - used to evaluate of animal's basal activity and its evolution for...
An entirely modular experimental enclosure designed to conduct operant conditioning procedures...
A standard experimental chamber for automated or manual assessment of conditioned place...
Real-Time Physiological Monitoring for Small Animals – Wireless & Non-Invasive The Bioseb...
The ETH-401 is a bridge amplifier for various transducers that provides four channels of...
The IX-118 is a fast 100 Khz, high-resolution data acquisition system suitable for most data...
The ETH-256 is a 2 channels high performance, general-purpose life science research amplifier,...
Discover BIO-FOODIS, the next generation solution for understanding animal feeding behavior with...
The OXYLET system - Physiocage is a modular system allowing the integration of respiratory...
Innovative and appropriate equipment for measuring food/liquid consumption and correlated motor...
An economical, high performance Oxygen and Carbon Dioxide Analyzer with sampling rates fast...
The BIOSEB Spontaneous Activity Wheel offers an effective solution for quantifying rodent voluntary activity within their home cage environment. The embedded electronics provide a wide range of measurements including wheel revolutions, average/min/max speed, acceleration, utilization time, access events, and more. The Premium model expands on these standard features, enabling animal filming and task complexity enhancement by removing bars. Beyond neuromuscular diseases, this tool also facilitates the study of neurodegenerative disorders, including Parkinson's, Huntington's, and ALS.
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Presentation
Bioseb’s wheels are easy-to-use, time-efficient and reliable. Thanks to their large cage size allowing standard bedding and free access to Food/Drink, a single animal can be housed for an extended period of time. Animals benefit from free access to a running wheel featuring a large diameter for comfortable and natural exercise. In addition to the transparent living cages enabling long-term monitoring of the animals, the combination of a coded disc with an electronic sensor allows you to record parameters pertaining to the voluntary running of animals, who freely decide upon exercise timing and intensity. With the best accuracy on the market (22.5°), the rotation disc allows for the capture of very short laps events (Play/curiosity events) and accurate recording of accelerations (calculated in the optional software).
Measurements include the distance run in both directions, the number of wheel revolutions, average/min/max speed, acceleration, total time in the wheel, number of access events, and can be displayed in statistical form or sorted by custom time periods. Spontaneous Activity Wheels are an ideal tool for studies on Drug Screening, Phenotyping, Circadian Rhythms, Neuromuscular Diseases and also Parkinson disease, Huntington disease and Amyotrophic lateral sclerosis.
Operating principle

Highly reliable sensors offer an excellent angular resolution (22°) and time resolution (0.1 seconds) to accurately record spontaneous exercising behavior, even allowing the study of subject acceleration and power pattern.
A complete digital solutionis provided by Bioseb’s ACTIVW-SOFT software allowing you to monitor up to 64 cages simultaneously via an external connection to the PC USB port (up to 5 m between cage and PC).
Data sheet
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[title] => DSOK-0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity-Based Anorexia Model
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[title] => TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration
[paragraph_crop] => TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse [...]
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[title] => PGE2 and EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib
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[image_presente] => 1
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[title] => Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats
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[title] => The search for translational pain outcomes to refine analgesic development- Where did we come from and where are we going?
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[title] => Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
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[title] => Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy
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[title] => Peripherally Acting _-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats
[paragraph_crop] => Peripherally Acting _-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and [...]
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[title] => The Ca2 influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
[paragraph_crop] => The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant [...]
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[date] => 2017-09-07 00:00:00
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[title] => Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats-
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[title] => Systems proteomics of liver mitochondria function
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[date] => 2016-06-10 00:00:00
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[title] => Miscellaneous research domains
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[url] => https://bioseb.com/en/news/the-clinical-heterogeneity-of-coenzyme-q10-deficiency-results-from-genotypic-differences-in-the-coq9-gene-n791
[title] => The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene
[paragraph_crop] => The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in [...]
[image_presente] =>
[date] => 2015-03-23 00:00:00
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[title] => Phenotyping
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[title] => Inflammation-induced decrease in voluntary wheel running in mice- a nonreflexive test for evaluating inflammatory pain and analgesia-
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[image_presente] =>
[date] => 2012-04-30 00:00:00
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[title] => Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances-
[paragraph_crop] => Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
[image_presente] =>
[date] => 2009-08-12 00:00:00
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1Number of publications:
An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins,...
The BIOSEB Spontaneous Activity Wheel is an easy way to quantify rodent voluntary activity in their home cage environment....
The uncomplicated way to monitor rodent activity over several days from their home cage without manual...
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