Activity, Motor Control & Coordination
Pain - Thermal Allodynia / Hyperalgesia
Pain - Spontaneous Pain - Postural Deficit
Pain - Mechanical Allodynia / Hyperalgesia
Anxiety & Depression Disorder
Learning/Memory - Attention - Addiction
Physiology & Respiratory Research
Metabolism - Food & Drink Intake
Pain
Metabolism
Motor control
Neurodegeneration
Cross-disciplinary subjects
Muscular system
General activity
Mood Disorders
Other disorders
Joints
Central Nervous System (CNS)
Sensory system
Authors
NM Korthagen, HM de Visser, G Geusebroek, G Storm et al
Lab
Utrecht Univ., Utrecht, Netherlands
Journal
Osteoarthritis and Cartilage
Abstract
Local intra-articular injections with triamcinolone acetonide (TA) is favorable as an anti-inflammatory treatment. In animal (rat) models of OA it was shown that TA can reduce osteophyte formation and thus may be beneficial as a disease modifying treatment. To evaluate the potential for slow-release anti-inflammatory treatment in a model mimicking metabolically accelerated post-traumatic OA, we evaluated the effect of TA-loaded liposomes, in the high-fat diet groove model in rats.
BIOSEB Instruments Used:
Dynamic Weight Bearing 2.0 (BIO-DWB-DUAL)
