Capsazepine decreases corneal pain syndrome in severe dry eye disease

Authors
D Fakih, A Guerrero-Moreno, C Baudouin

Lab
Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012, Paris, France

Journal
Journal of Neuroinflammation

Abstract
Dry eye disease (DED) is a multifactorial disease of the ocular surface accompanied by neurosensory abnormalities. Here, we evaluated the effectiveness of transient receptor potential vanilloid-1 (TRPV1) blockade to alleviate ocular pain, neuroinflammation, and anxiety-like behavior associated with severe DED.

BIOSEB Instruments Used:
Elevated Plus Maze : EPM3C - 3 clicks only ! (BIO-EPM3C)