EFFECT OF 1-HYDROXY-1-1-ETHYLIDENDIPHOSPHONE ACID- BIS-2-PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS

Authors
Cheretaev I. V., Ravaeva M. Yu., Dzheldubaeva E. R, et al

Lab
V. I. Vernadsky Crimean Federal University, Simferopol, Crimea, Russia

Journal
Scientific notes of the Crimean Federal University named after V.I. Vernadsky

Abstract
The aim of the work is to evaluate the effect of 1-hydroxy-1,1-ethylidenediphosphonic acid, bis(2-pyridyl-1,2,4-triazolyl-3)propane and their adduct on the pain sensitivity of male rats in the dose range from 5 to 200 mg/kg.

BIOSEB Instruments Used:
Cold Hot Plate Test (BIO-CHP),Rodent pincher - analgesia meter (BIO-RP-M)