Activité, Système Moteur & Coordination
Douleur - Allodynie/Hyperalgésie Thermique
Douleur - Spontanée - Déficit de Posture
Douleur - Allodynie/Hyperalgésie Mécanique
Anxiété & Dépression
Apprentissage/Mémoire - Attention - Addiction
Physiologie & Recherche Respiratoire
Métabolisme & Prise Alimentaire
Douleur
Métabolisme
Système moteur
Neurodégénérescence
Thématiques transversales
Système musculaire
Functions de motricité générale
Troubles de l'humeur
Other disorders
Joints
Système Nerveux Central (SNC) 
Système sensoriel
Authors
C. L. Anderson, B. J. Tessler , T. B. DeMarse, M. Douglas-Escobar, C. Rossignol, R. Nelson, A. K. Kasinadhuni, M. King, P. Bose, M. D. Weiss, P. R. Carney
Lab
University of Florida, Crayton Pruitt Family Department of Biomedical Engineering, , Gainesville, Florida
Journal
Opne Access Text
Abstract
Prenatal cerebrovascular stroke can cause permanent damage to the brain followed by deficits in neuro-muscular functioning. We hypothesize that recovery can be enhanced by transcranial direct current stimulation (tDCS) through changes in cortical plasticity. Unilateral hypoxia-ischemia (HI) was produced in rats on postnatal day 7 (P7). At P21, anodal tDCS was given to HI pups for 7 days. tDCS treated HI pups showed improved weight, grip strength, gait, motor function, and concentrations of brain-derived neurotropic factor cortex ratios compared to non-treated HI animal controls. These findings support tDCS following HI as an effective therapeutic for neonatal stroke.
BIOSEB Instruments Used:
Grip strength test (BIO-GS3)
