Effect of 1-Hydroxy-1-1-thylidendiphosphone Acid- Bis-2-Pyridyl-1-2-4-Triazolyl-3-Propane and their adduct on the pain sensitivty of Rats

Authors
IV Cheretaev, MY Ravaeva, ER Dzheldubaeva et al

Lab
V. I. Vernadsky Crimean Federal University, Simferopol, Crimea, Russia

Journal
Biology Chemistry

Abstract
The aim of the work is to evaluate the effect of 1-hydroxy-1,1ethylidenediphosphonic acid, bis(2-pyridyl-1,2,4-triazolyl-3)propane and their adduct on the pain sensitivity of male rats in the dose range from 5 to 200 mg/kg.

BIOSEB Instruments Used:
Cold Hot Plate Test (BIO-CHP),Rodent pincher - analgesia meter (BIO-RP-M)