Impact of SEL1L deletion in central nervous system on the behavior of mice

Authors
J Wang, Q Liu, Z Pan, Z Zhou, Q Long

Lab
Research Center of Laboratory Animals and the Genome Rseearch center of Cambridge-Soochow University, Suzhou, China

Journal
Chinese Journal of Comparative Medicine

Abstract
The Objective was to investigate the role of endoplasmic reticulum protein SEL1L in the maintenance of physiological activities of the central nervous system in mammals. The data of the postnatal survival time, the body weight and the behavioral indicators such as balance coordination, locomotion and anxiety of the mice show that the condition of the NKO mice is significantly worse than that of the WT mice, indicating an important role of SEL1L in the maintenance of physiological functions of the nervous system.

BIOSEB Instruments Used:
Grip strength test (BIO-GS3)